Multiple choice questions

1)    A synthetic nucleotide analogue, used during organ transplantation as a immunosuppressant to avoid immunologic rejection of grafts is

(A)  Theophylline

(B)   Cytarabine

(C)   6-Mercaptopurine

(D)  4-Hydroxypyrazolopyrimidine

2)    Carbonic anhydrase enzyme has maximum turn over number (i.e. 36 million). Minimum turn over number for an enzyme:

(A)  DNA polymerase

(B)   Lysozyme

(C)   Penicillase

(D)  Lactase dehydrogenase

3)    Hemolytic anemia is caused by the deficiency of a specific enzymes of the pentose phosphate pathway, the principal enzyme involved is

(A)  Glucose-6-phosphate dehydrogenase

(B)   Aldolase

(C)   Fructose 1, 6-bisphosphatase

(D)  Phosphohexose isomerase

4)    Which of the following is a microsomal enzyme inducer?

(A)  Indomethacin

(B)   Clofibrate

(C)   Glutethamide

(D)  Tolbutamide

5)    Dry seeds survive on higher temperature than germinating seeds as

(A)  Hydration is essential for making enzymes sensitive to temperature

(B)   Dry seeds have a hard covering

(C)   Dry seeds have more reserve food

(D)  Seedlings are tender

6)    Covalent modification of an enzyme usually involves phosphorylation/ dephosphorylation of

(A)  Serine residue

(B)   Proline residue

(C)   Hydroxylysine residue

(D)  Hydroxyproline residue

7)    Which of the following enzyme typically elevated in alcoholism?

(A)  Serum ALP

(B)   Serum GOT

(C)   Serum g-GT

(D)  None

8)    The glycogen content of the liver is upto

(A)  6% (B) 8%

(B)   10% (D) 12%

9)    Acute hemolytic episode after administration of antimalarial, primaquin, is due to deficiency of the enzyme:

(A)  6-Phosphogluconate dehydrogenase

(B)   Glucose-6-phosphate dehydrogenase

(C)   Epimerase

(D)  Transketolase

    10)  Which of the following is known as bone forming enzyme?

(E)   Alkaline phosphatase

(F)    Acid phosphatase

(G)  Leucine aminopeptidase

(H)  none

Answers 1-C, 2-B, 3-A, 4-C, 5-A, 6-A, 7-C, 8-B, 9-B, 10-A