Virus classification

Phylum incertae sedis

Order Nidovirales

Family Coronaviridae

Subfamily Orthocoronavirinae

Genus Alphacoronavirus (Alpha-CoV)

Betacoronavirus (Alpha-CoV)

Gammacoronavirus (Alpha-CoV)

Deltacoronavirus (Alpha-CoV)

Species of Alphacoronavirus

Human coronavirus 229E, Human coronavirus NL63, Miniopterus bat coronavirus 1 etc.

Species of Betacoronavirus

Human coronavirus HKU1, Severe acute respiratory syndrome-related coronavirus (SARS-CoV), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), Middle East respiratory syndrome-related coronavirus (MERS) etc.

Species of Gammacoronavirus

Infectious bronchitis virus etc.

Species of deltacoronavirus

Bulbul coronavirus HKU11 etc.

There are seven strains of human coronavirus, four strains of which produce the generally mild symptoms of the common cold:

1. Human coronavirus OC43 (HCoV-OC43)

2. Human coronavirus HKU1

3. Human coronavirus NL63 (HCoV-NL63, New Haven coronavirus)

4. Human coronavirus 229E (HCoV-229E)

and three strains cause severe symptoms:

1. Middle East respiratory syndrome-related coronavirus (MERS-CoV), previously known as novel coronavirus 2012 and HCoV-EMC

2. Severe acute respiratory syndrome coronavirus (SARS-CoV or "SARS-classic")

3. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), previously known as 2019-nCoV or "novel coronavirus 2019"

Some interesting facts about SARS-CoV2:

· Previously it was known as 2019 novel coronavirus (2019-nCoV)

· SARS-CoV2 is responsible for pandemic COVID-19

· Outbreak of SARS-CoV2 is declared as pandemic by WHO on March 11, 2020.

· It is the seventh known coronavirus to infect people, after 229E, NL63, OC43, HKU1, MERS-CoV, and the original SARS-CoV.

· Its transmission occurs by respiratory droplets like cough and sneeze within the range of 2 metre.

· Size of SARS-CoV2 is 50-200nm in diameter.

· SARS-CoV-2 has four structural proteins, known as the S (spike), E (envelope), M (membrane), and N (nucleocapsid) proteins; the N protein holds the RNA genome, and the S, E, and M proteins together create the viral envelope.

· Spike protein is responsible for attachment of virus to host membrane.

· Genome of SARS-CoV2 is positive-sense single-stranded RNA (+ssRNA).

· Its genome is of 30kb length.

· SARS-CoV2 bind with angiotensin converting enzyme2 (ACE2) receptors of human cells and enter into cells.

COVID-19 Update (till March 22, 2020 at 7:00 PM IST)

Total Coronavirus Cases: 317,298

Deaths:13,642

Recovered: 95,949

Active cases		Closed cases
207,707 Currently Infected Patients		109,591 Cases which had an outcome:
197,565 (95%) in Mild Condition	10,142 (5%) Serious or Critical	95,949 (88%) Recovered / Discharged	3,642 (12%) Deaths

COVID-19 Update (till March 22, 2020 at 5:30 AM IST)

Total cases	New cases	Total deaths	New deaths	Total recovered	Active cases	Serious, critical	Total cases/1M population
360	28	7	2	24	329		0.3